Phytoconstituents, Antioxidant and Antimicrobial Activities of Livistona chinensis (Jacquin), Saribus rotundifolius (Lam.) Blume and Areca catechu Linnaeus Nuts

 

Emmanuel E. Essien*, Bassey S. Antia, Esangubong I. Etuk

 Department of Chemistry, University of Uyo, 520101, Akwa Ibom State, Nigeria

Abstract

Livistona chinensis, Saribus rotundifolius and Areca catechu are palms primarily cultivated for ornamental purposes and also utilized in herbal remedies. The chemical and biological studies were conducted using standard procedures. Phytochemical screening revealed the presence of alkaloids, saponins, cardiac glycosides, terpenes, de-oxy sugars, anthraquinones, phenols, flavonoids and phlobatannins in varying amounts. The total phenolics content ranged from 52.0-245.0 mg/g, DPPH radical inhibition (87.30-90.55%, 2.0 mg/ml), iron chelating activity (27.3-65.0%, 0.5 mg/ml), hydrogen peroxide scavenging (93.18-98.46%, 0.5 mg/ml), and molybdate ion reduction capacity (15.93-58.30%, 0.5 mg/ml). L. chinensis extract showed notable antimicrobial activity against B. subtilis, P. aeruginosa and C. albicans (MIC = 75-100 µg/ml) while A. catechu and S. rotundifolius extracts were potent against all test pathogens (75-100 µg/ml), except S. typhi (150 µg/ml). However, no appreciable cytotoxic effects on human cervical (HeLa), lung (H460), breast (MCF-7) and prostate (PC-3) cancer cells at 30 µg/mL was observed for the extracts. The notable antioxidant and antimicrobial activities of the palm extracts are a function of their inherent bioactive constituents and a potential source of medicinally useful compounds. The chemical and biological assessment of S. rotundifolius palm nuts is reported for the first time.

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Pharmacognostic and Preliminary Phytochemical Evaluation of Centipeda minima and Bauhinia purpurea Leaves 

 

Ashish Sarkar1*, Vijay Dutt Tripathi2, Ram Kumar Sahu3, Erwin Martinez Faller4

1Institute of Pharmacy, HCPG College, Varanasi, Uttar Pradesh, India

2Sagar Institute of Technology, Lucknow, Uttar Pradesh, India

3Columbia Institute of Pharmacy, Tekari, Raipur, Chhattisgarh, India

4School of Pharmacy, Management & Science University, Selangor Darul Ehsan, Malaysia

Abstract

Centipeda minima and Bauhinia purpurea are used as traditional medicinal plant for ailment of various diseases. The present study was aimed to evaluate the Pharmacognostic and Phytochemical screening ofCentipeda minima and Bauhinia purpurea. The Pharmacognostic evaluation (total ash, acid insoluble ash, water soluble ash, water soluble extractive and alcohol soluble extractive) and fluorescence analysis of leaves powder were performed. Preliminary phytochemical investigation was carried out of the crude extracts of Centipeda minima and Bauhinia purpurea leaves using solvents of different polarity. The Pharmacognostic characters of Centipeda minima and Bauhinia purpurea have been done for standardization of crude drug. The results of preliminary phytochemical revealed the presence of flavonoids, tannins, phenolic compounds, alkaloids, glycosides, fats and carbohydrates in Centipeda minima and Bauhinia purpurea leaves.These studies provided referential information in regard to its identification parameters assumed significantly in the way of acceptability of herbal drugs in present scenario of lack of regulatory laws to control quality of herbal drugs.

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Phytochemical Screening and Antioxidant Activity of Ethanol Extract of Psoralea corylifolia seeds

 

Nelofar Gulam Nabi*, Mukta Shrivastava

Govt. Maharani Laxmi Bai Girls` P.G. (Autonomous) College, Bhopal (M.P)-462002, India

Abstract

Flavonoids are a group of polyphenolic compounds, which are widely distributed throughout the plant kingdom. Flavonoids of different classes exhibited various pharmacological and biological activities. The present study was undertaken to investigate the total flavonoids and antioxidant effect of Psoralea corylifolia seeds. The ethanol extract of Psoralea corylifolia seeds were prepared and performed its phytochemical screening. The total flavonoids and polyphenol were investigated to quantify the presence of polyphenol compounds. The 2, 2- diphenyl-1-picryl-hydrazil stable radical (DPPH) and Superoxide scavenging radical were used to determine extract antioxidant activity. The concentrations of flavonoids and polyphenol in ethanol extract of Psoralea corylifolia seeds were 60.63 QE. mg/gm and 74.35 GAE mg/gm respectively. The extract exhibited the strongest antioxidant activity with the lowest IC50 - value for DPPH and Superoxide scavenging. The IC50 value for DPPH and Superoxide scavenging were 166.61 μg/ml and 177.69 μg/ml respectively. The strongest antioxidant activity of ethanol extract could be due to the presence of flavonoids and phenols.

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In Vitro Impact of Laser Irradiation on Platelets Aggregation 

 

Eman A. Shakir 

Department of physiology, College of Medicine, Almustansyria University, Baghdad-10052, Iraq

Abstract

The review of blood optical and rheological parameters played an important role in many medical routine diagnosis and therapeutic applications, and it is the best design to understand the mechanism of action of the low level laser irradiation on biological tissues. The insistence of this study was to investigate the in vitro effect of laser radiation on platelets number and aggregation. The blood samples were conquered from 30 healthy volunteers, each sample was parted into four aliquots one of them was considered as control while the other three were exposed to three different laser doses. The wavelength of 532 nm was used for irradiation with 4 mm diameter beam spot. The irradiation times were 1.8, 3.7 and 6.2 sec giving different doses of irradiation 1.5, 3 and 5 J/cm2, respectively. Low laser irradiations induce significant changes in platelets aggregation in presence of weak agonist as ADP (P≤0.05) and epinephrine (P≤0.01). Low-level laser therapy has no influence on platelets count; however, its promote platelets aggregation in response to weak agonist, specifically ADP and epinephrine. 

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